RHEUMATOID ARTHRITIS.
RHEUMATOID ARTHRITIS DEFINITION – Rheumatoid arthritis is a chronic, autoimmune, progressive, inflammatory disease , affecting joints and periarticular tissues. – Inflammatory mediators are released in joints which initiates inflammatory process. – Earliest lesion is vasculitis, then synovial edema and infiltration with inflammatory cells . – Local prostaglandin synthesis occurs which causes vasodilation and …